Events Archives

AMAP Annual General Meeting

Tuesday October 3rd, 2017 10am - 4pm, Brain Repair Centre

With keynote speaker, Dr Francesco Roselli, University of ULM, Germany
"Understanding mesoscale non-cell-autonomous processes in ALS"

10.00 Introductions

10.30 Keynote Speaker

11.30 Working Lunch

12.30 Presentations - schedule below


Lab Group





Olivier Laflamme

PhD student, Medical Neuroscience



Kristin Ko

MASc student, Biomedical Engineering



Angelo Iulianella

Associate Professor, Medical Neuroscience



Melissa O’Brien

PhD student, Pharmacology and Anaesthesia






Tom Landry

Research Associate, EAR Lab



Julia Harrison

PhD student, Medical Neuroscience



Dylan Deska-Gaulthier

PhD student, Medical Neuroscience



Antonios Diab

PhD student, Pharmacology







Closing remarks



Atlantic Mobility Action Project Journal Club Meetings

The Atlantic Mobility Action Project Journal Club gathers researchers, students and technical staff with an interest in the neurobiology of the brain and spinal cord and the underpinnings of potential treatments for movement disorders. Funded by the Brain Repair Centre, the club provides a venue for informal discussions of scientific publications broadly related to ongoing research projects and may include such topics as neurodevelopment, neural circuitry underlying locomotion, spinal cord and brain injury, and neuromuscular disorders. Meetings provide an opportunity for participants to share new findings and techniques, break down complex concepts, and find new ways to further their research. Students report that taking part in the journal club discussions enhances their presentation skills and helps prepare them for their all-important thesis defence.

Papers from recent meetings:

March 16, 2017 - Local Spinal Cord Circuits and Bilateral Mauthner Cell Activity Function Together to Drive Alternative Startle Behaviors
February 2, 2017 - In Vivo Interrogation of Spinal Mechanosensory Circuits
December 1, 2016 - Capturing and Manipulating Activated Neuronal Ensembles with CANE Delineates a Hypothalamic Social-Fear Circuit
October 13, 2016 - RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS
June 15, 2016 - Inhibitory Input from the Lateral Hypothalamus to the Ventral Tegmental Area Disinhibits Dopamine Neurons and Promotes Behavioral Activation 
June 2, 2016 - Neural progenitor cell transplantation promotes neuroprotection, enhances hippocampal neurogenesis, and improves cognitive outcomes after traumatic brain injury
May 19, 2016 - Electronic dura mater for long-term multimodal neural interfaces
May 5, 2016 - Astrocyte scar formation aids central nervous system axon regeneration
April 7, 2016 - Cell Type-Specific Circuit Mapping Reveals the Presynaptic Connectivity of Developing Cortical Circuits
March 10, 2016 - Context-Dependent Gait Choice Elicited by EphA4 Mutation in Lbx1 Spinal Interneurons
February 25th, 2016 - Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SODG93A mice co-expressing the Copper-Chaperone-for-SOD
February 11 2016 - Muscle-type Identity of Proprioceptors Specified by Spatially Restricted Signals from Limb Mesenchyme
January 14, 2016 - Essential role for ligand-dependent feedback antagonism of vertebrate hedgehog signaling by PTCH1, PTCH2 and HHIP1 during neural patterning
December 3, 2015 - Activating Injury-Responsive Genes with Hypoxia Enhances Axon Regeneration through Neuronal HIF-1α
November 19, 2015 - 3D Reconstitution of the Patterned Neural Tube from Embryonic Stem Cells
November 5, 2015 - A genetically defined asymmetry underlies the inhibitory control of flexor–extensor locomotor movements
October 22, 2015 - Imaging multiple phases of neurodegeneration: a novel approach to assessing cell death in vivo
October 8, 2015 - Spinal Locomotor Circuits Develop Using Hierarchical Rules Based on Motorneuron Position and Identity
May 21, 2015 - Early and Persistent Abnormal Decoding by Glial Cells at the Neuromuscular Junction in an ALS Model
May 7, 2015 - Spine pruning drives antipsychotic-sensitive locomotion via circuit control of striatal dopamine
April 23, 2015 - Neuegulin-1 is concentrated in the postsynaptic subsurface cistern of C-bouton inputs to α-motoneurons and altered during motoneuron diseases (.pdf to be emailed to club members)
April 9, 2015 - Identification of a cellular node for motor control pathways
March 26, 2015 - Directional Notch trafficking in Sara endosomes during asymmetric cell division in the spinal cord
March 12, 2015 - A motor cortex circuit for motor planning and movement
February 26, 2015 - Overexpression of Sox11 Promotes Corticospinal Tract Regeneration after Spinal Injury While Interfering with Functional Recovery
February 12, 2015 - Identification of a spinal circuit for light touch and fine motor control
January 29, 2015 - Systematic Shifts in the Balance of Excitation and Inhibition Coordinate the Activity of Axial Motor Pools at Different Speeds of Locomotion
December 4, 2014 - Delayed Disease Onset and Extended Survival in the SOD1G93A Rat Model of Amyotrophic Lateral Sclerosis after Suppression of Mutant SOD1 in the Motor Cortex
November 20, 2014 - Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts
November 6, 2014 - Serotonin Affects Movement Gain Control in the Spinal Cord
October 16, 2014 - Coordination of progenitor specification and growth in mouse and chick spinal cord 
September 25, 2014 - Necroptosis drives motor neuron death in models of both sporadic and familial ALS
September 16, 2014 - Neuronal Ig/Caspr Recognition Promotes the Formation of Axoaxonic Synapses in Mouse Spinal Cord
June 3, 2014 - Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development
May 20, 2014 - V1 and v2b interneurons secure the alternating flexor-extensor motor activity mice require for limbed locomotion.
April 29, 2014 - Restoring Voluntary Control of Locomotion after Paralyzing Spinal Cord Injury
April 15, 2014 - Optical Control of Muscle Function by Transplantation of Stem Cell Derived Motor Neurons in Mice
April 1, 2014 - Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons
March 18, 2014 - Dendrite Self-Avoidance Requires Cell-Autonomous Slit/Robo Signaling in Cerebellar Purkinje Cells
March 4, 2014 - Motor-Circuit Communication Matrix from Spinal Cord to Brainstem Neurons Revealed by Developmental Origin
February 18, 2014 - Locomotor Rhythm Generation Linked to the Output of Spinal Shox2 Excitatory Interneurons
February 4, 2014 - Defects in synapse structure and function precede motor neuron degeneration in Drosophila models of FUS-related ALS
January 21, 2014 - Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification
January 7, 2014 - MINK and TNIK Differentially Act on Rap2-Mediated Signal Transduction to Regulate Neuronal Structure and APMA Receptor Function
December 10, 2013 - A method for the three-dimensional reconstruction of Neurobiotin-filled neurons and the location of their synaptic inputs

To access any of these papers, please visit the Brain Repair Centre website.

Mind into Matter symposium set for Halifax, May 2014

Mind into Matter: Bodies and Space is a platform for the beginnings of an interdisciplinary exchange of critical scholarship and creative practice in the field of body-environment relationships. The three-part event is being staged at Dalhousie University on May 9 and 10, 2014, It includes a symposium, exhibition, and performance, and engages practitioners from the arts, sciences, and design fields.

Halifax to host 2014 international motoneuron conference

The 9th International Motoneuron Meeting will take place from June 15 to 19, 2014, at Dalhousie University in Halifax, N.S. This meeting brings together scientists, clinician-investigators and students with a shared research focus on motor neuron diseases.

2014 conference organizers, Dr. Rob Brownstone and Dr. Jim Fawcett, were recently successful in their application to the Brain Repair Centre for the Scotiabank-BRC Research, Dissemination and Commercialization Grant. This grant, sponsored by Scotiabank, will help them organize the Halifax conference.

The National Institute of Neurological Disorders and Stroke is a major sponsor of the 2014 International Motoneuron Meeting.

Halifax to host 2013 Canadian spinal cord conference

Spinal cord researchers from across Canada will converge on Halifax in April 2013 to share their latest findings and new research directions in the pursuit of solutions to problems caused by damage to the spinal cord and its neural circuits. "The Spinal Cord: Functional Restoration and Repair" conference will take place at the Halifax Marriott Harbourfront hotel from April 21 to 23.
Click here for more information about this conference.

Visiting Guest Speaker

Gareth Miles
University of St. Andrew's, UK
Neuromodulation of Spinal Motor Networks: Beyond Putting the Best Foot Forward
Thursday, April 7, 2011, 2:30-3:30 RM 14B2, Tupper Building

Clinician Scientist Visiting Speakers Program - 2011

Jack Feldman, PhD
David Geffen School of Medicine at UCLA
Distinguished Professor, Neurobiology
Looking for Inspiration
May 25, 2011, 2:00-4:00 pm
Theatre A, Tupper Bldg

Shawn Hochman, PhD, Associate Professor
Department of Physiology, Emory University  
“Restless Leg Syndrome”
Wednesday, March 9, 2011 08:30-09:30 hrs
Royal Bank Theatre, Halifax Infirmary
“Limiting body sensations by presynaptic inhibition: New vistas”
Wednesday, March 9, 2011 2:30-4:00 pm
Rm 14B2, Tupper Bldg.